Commentary to provide context and explain significance of research is sometimes just as important as the research itself. That’s why our experts make it a priority to provide you with helpful content distilled from the many years of experience our team has accumulated. The Drug Development Insights blog contains overviews and deep dives into the drug metabolism and pharmacokinetics topics you care about—regulatory expectations, risk assessment, safety considerations, scientific innovation, study design elements, interpretation of results, and more. Explore our entries chronologically or by category to get insight into the many pieces of your drug’s development.
Drug Development Blog
Four Ways CROs Drive Innovation for Improved In Vitro Drug Metabolism and Pharmacokinetics (DMPK) Studies
- Drug Metabolism
- May 17, 2021
- Darina Hynes, Madison Esely-Kohlman
Agility and focused growth allow drug developers to outsource expertise and benefit the industry at-large by fostering innovation. Panelists at the 2021 Annual DMDG Meeting highlighted the importance of...
DDI & Drug Repurposing Article featured in Drug Discovery World (DDW) Spring Edition 2021
- Drug Drug Interactions (DDI)
- April 29, 2021
- Madison Esely-Kohlman, Dr. Brian Ogilvie
Repurposing (repositioning, re-profiling, or re-tasking) a drug potentially saves years of costly testing from going to waste and potentially providing a higher chance of success.…
Meet the Scientist: Stephanie Helmstetter
- Meet the Scientist
- February 20, 2021
- Madison Esely-Kohlman
As part of our Meet the Scientist series, we introduce you to one of our most notable product experts, Stephanie Helmstetter.
Interview with Outsourcing Pharma: Repurposing existing drugs accelerates discovery
- Consultancy
- January 18, 2021
- Madison Esely-Kohlman
“Exploring alternative uses for drugs tapped for other indications, can save considerable time and money in discovery, according to an...
Meet the Scientist: Lois Haupt
- Meet the Scientist
- November 6, 2020
- Madison Esely-Kohlman
As part of our Meet the Scientist series, we introduce you to one of our most notable Enzyme Inhibition experts, Lois Haupt.
Updated Look & Fresh Features: Welcome to Our Brand New Website!
- Updated Offerings
- September 18, 2020
- Madison Esely-Kohlman
We are thrilled to welcome you to the brand new XenoTech website! The reconstruction project is a massive overhaul of over 1,000 pages carefully recrafted…
Drug-Drug Interaction (DDI) Prediction Models Following In Vitro Studies in Preclinical Development
- Drug Drug Interactions (DDI)
- August 12, 2020
- Madison Esely-Kohlman, Dr. Pallavi Limaye, Andrea Wolff, Dr. Maciej Czerwinski
In preclinical development, a drug will be evaluated for potential to cause a drug-drug interaction (DDI) using in vitro experiments and then calculations that...
Toxicokinetic (TK) Analysis for Preclinical Drug Development
- In Vivo & Radiolabeling
- August 6, 2020
- Madison Esely-Kohlman, Jolanta Golec, Dr. Pallavi Limaye
The main goal of preclinical toxicokinetic (TK) studies is to establish a correlation between a candidate compound’s concentration or dose...
XenoTech Named Most Innovative Drug Development Solutions Provider – USA 2020
- Accomplishments
- August 3, 2020
- Michael Millhollen
The 2020 Technology Innovator Awards returns for its fifth year “to reward those talented and dedicated individuals and firms working...
Important DDI Considerations for Repurposing Drugs to Treat COVID-19
- Drug Drug Interactions (DDI)
- June 8, 2020
- Madison Esely-Kohlman
“Given the rapid spread of COVID-19 and its relatively high mortality, filling the gap for coronavirus-specific drugs is urgent. […]...
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