Tox
Why You Need QWBA for Human Radiolabeled ADME Studies
A quantitative whole body autoradiography (QWBA) study provides data required for Human Radiolabeled ADME Studies1. Quantitative whole body autoradiography (QWBA) is an in...
How to Choose the Right Test Systems for Your DMPK Studies
Test systems for DMPK in vitro studies are part of the very foundation of our company. Our labs were borne of...
In Vitro Induction Studies: Elements of Design and Important Considerations in Data Analysis
Why do induction studies? Induction potential is an important piece of the drug-drug interaction (DDI) component of an IND submission. Simply put, we...
Minding Your Binding: Plasma Protein Binding Potential Study Now Available at Our US Labs
While liver and intestine are important in ADME, behavior in blood is also crucial. When an orally administered drug or...
Studies in Japan: Easier & More Beneficial than You Might Think
XenoTech is well-known to pharmaceutical companies and toxicology academics alike for unparalleled experience in quality in vitro ADME/DMPK/DDI studies and complementary products,...
Can Interactions Between Therapeutic Proteins and Small Molecule Drugs Be Evaluated In Vitro?
The mechanisms of clearance for small molecule drugs and therapeutic proteins are fundamentally distinct and therefore therapeutic proteins are generally not...
Important Considerations for the Conduct of In Vitro Drug Transporter Assays
Not only can drug transporters affect the absorption and excretion of drugs, they can be involved in pharmacokinetic-based drug-drug interactions...
To GLP or not to GLP?
That is the question. . . Knowing the answer may save you time and money Good Laboratory Practices (GLP) are...
Choosing a Relevant Small Animal Model for Pharmacokinetic or Toxicity Studies
Choosing the most suitable small animal model is crucial for pharmacokinetic and/or toxicology studies in order to get usable, relevant data. Due to potential...
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