In Vitro Evaluation of Immunomodulating Drugs as Perpetrators of Drug Interactions
Presenter: Dr. Maciej Czerwinski, XenoTech Director of Consulting
Synopsis: On October 15th, 2018, XenoTech presented on “In Vitro Direct and Cytokine-Mediated Effects of Therapeutic Peptides and other Biologics on CYP Enzymes” at the Peptide ADME Discussion Group Workshop in Gothenburg, Sweden. Following subsequent requests for a follow-up webinar, Dr. Czerwinski will be presenting on the following subjects…
Key concepts discussed in this webinar will include:
- Immunomodulators
- Mechanisms of immunomodulator drug-drug interactions (DDI)
- Regulatory guidance on evaluating DDI potential of biologics
- Study design to evaluate direct and cytokine-mediated effects of immunomodulators on drug metabolizing enzymes
- Case studies of experiments conducted according to our study design…
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