Webinars
ADME 101: Considerations & Calculations When Sending In Vitro Test Articles
Presenter: Patrick McAnulty, XenoTech Scientist II, Program Design This ADME 101 webinar discusses the #1 most frequently asked question that our Protocol Design team receives:...
The Basics of In Vitro Xenobiotic Metabolism and Drug-Drug Interaction Investigations: Applicability to All Xenobiotics
Since SOT’s 59th Annual Meeting and ToxExpo has been canceled due to COVID-19 concerns, we are bringing the tradeshow to you! SOT is hosting this...
ADME 101 FAQ: Tips & Tricks for Working with Plateable Hepatocytes
Presenter: Halee McElhaney, XenoTech Team Lead, Quality Control In the latest installment of ADME 101, one of our hepatocyte experts answers frequently asked questions about plateable...
ADME 101: Metabolite ID & Characterization Studies FAQ
Presenter: Mark Horrigan, XenoTech Principal Scientist, Program Oversight In this short, information-packed ADME 101 video, one of our study directors discusses the main frequently asked questions...
Drug Metabolism Related Safety Considerations in Drug Development
Approximately 30 years ago, sub-optimal DMPK properties were recognized as the primary contributor to the failure (~40%) of potential new therapies in early clinical trials. This observation precipitated a renaissance period across the discipline which served to align DMPK efforts within discovery to assist in selecting optimal drug candidates to advance to clinical testing...
ADME 101: DMPK and ADME in Drug Development
Presenter: Joanna Barbara, Ph.D., Vice President of Scientific Operations at XenoTech We are pleased to present XenoTech’s first ADME 101 series webinar, Acronyms Abound: DMPK and...
Transporters of Emerging Importance in Drug Development: Beyond the Guidance Documents
Presenter: Brian Ogilvie, Ph.D., XenoTech Vice President of Scientific Consulting Synopsis: In October, 2017, the US FDA revised and split its 2012 draft guidance for industry...
In Vitro Induction Studies: Elements of Design and Important Considerations in Data Analysis
In this webinar, Dr. Joanna Barbara will address frequently asked questions from sponsors seeking induction studies and elaborate on some recommendations we give to achieve successful regulatory submission. Points of discussions will include an overview of enzyme induction studies and critical considerations in design, from determination of supporting data to conclusive interpretation...
In Vitro Evaluation of Immunomodulating Drugs as Perpetrators of Drug Interactions
Presenter: Dr. Maciej Czerwinski, XenoTech Director of Consulting; Synopsis: On October 15th, 2018, XenoTech presented on “In Vitro Direct and Cytokine-Mediated Effects of Therapeutic Peptides and other Biologics on CYP Enzymes” at the Peptide ADME Discussion Group Workshop...
Understanding P-gp & BCRP Inhibition Assay Design & Outcomes
In vitro drug transporter inhibition studies are recognized for their importance due to the major role transporters play in absorption, distribution and excretion of compounds, and the toxicological and pharmacological consequences of transporter-mediated drug-drug interactions (DDI). P-gp and BCRP transporters limit intestinal absorption and blood-brain barrier penetration, and facilitate excretion into bile and urine...
What topic would you like to hear about?
Our experts are constantly on the hunt for new and exciting topics to present on, and nothing helps us figure out what you want to hear more than requests and feedback! Use our form to submit your request so we can continue producing educational materials you look forward to
