Scientific Posters

Full Title Automated High Content Drug Transport Screening with Transwell Plates for Drug Discovery Abstract The purpose of this study was to develop a method...

Full Title In vitro characterization of human liver lysosomes isolated from fresh tissue Abstract Evaluation of lysosomal catabolism is an integral part of the development...

Full Title Efficient use of chimeric mice with humanized livers for drug development support Abstract Chimeric mice with humanized livers can be used to obtain...

Full Title Evaluation of Chemical Inhibitors for UDP-glucuronosyltransferase (UGT) Reaction Phenotyping Assays in Human Liver Microsomes Abstract In the development of a new chemical entity (NCE)...

Full Title Comparison of Ki and IC50 Values for Prototypical Inhibitors of the Human ABC Transporters P-gp and BCRP in Membrane Vesicles Abstract P-gp (ABCB1/MDR1) and...

Full Title Comparative Investigation of Benzoapyrene, Procaine and Nevirapine Metabolism in Human Hepatocytes Abstract Skin metabolism is an important contributor to the safety and efficacy...

Full Title UGT Inhibition Studies in the Presence or Absence of Alamethicin: Evaluation of UGT1A1 and UGT2B7 Inhibition in Human Liver Microsomes and Recombinant Enzymes...

Full Title The Impact of Various Solvents and Solvent Concentrations on In Vitro Enzyme Induction Assessment Abstract Induction of cytochrome P450 (CYP) enzymes is one...

Full Title Effects of Albumin-Fused Human Growth Hormone TV-1106 on CYP Enzyme Expression in Human Hepatocytes Abstract Drug-drug interactions involving therapeutic proteins that can modulate...

Full Title In Vitro Assessment of the Drug-Drug Interaction of Rasagiline and Its Metabolite Aminoindan Abstract Rasagiline mesylate (PAI) is the active pharmaceutical ingredient of...